Drug reference
everolimus
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (TK Inhibitors)
Mechanism of action
Inhibitor of mammalian target of rapamycin (mTOR), a serine-threonine kinase; in several cancers and tuberous sclerosis complex, the mTOR pathway is dysregulated; everolimus binds to FKBP-12, an intracellular protein and thus inhibiting the mTOR kinase pathway
Common side effects
- Asthenia
- Constipation
- Fatigue
- Infection
- Cough
- Stomatitis
- Diarrhea
Known interactions (28)
- amiodarone + everolimus Major
- aprepitant + everolimus Major
- clarithromycin + everolimus Major
- dronedarone + everolimus Major
- everolimus + ketoconazole Major
- everolimus + measles mumps and rubella vaccine Major
- everolimus + nilotinib Major
- everolimus + phenytoin Major
- everolimus + voriconazole Major
- atorvastatin + everolimus Moderate
- chloramphenicol + everolimus Moderate
- clotrimazole + everolimus Moderate
- dasatinib + everolimus Moderate
- efavirenz + everolimus Moderate
- erythromycin + everolimus Moderate
- everolimus + fluconazole Moderate
- everolimus + fluvoxamine Moderate
- everolimus + griseofulvin Moderate
- everolimus + hepatitis a vaccine inactivated Moderate
- everolimus + lapatinib Moderate
- everolimus + lovastatin Moderate
- everolimus + miconazole Moderate
- everolimus + nevirapine Moderate
- everolimus + nicardipine Moderate
- everolimus + pneumococcal vaccine 13-valent Moderate
- everolimus + ranolazine Moderate
- everolimus + felodipine Minor
- everolimus + nifedipine Minor
Related conditions
Frequently asked questions
What drug class is everolimus?
everolimus belongs to: Oncology.
How does everolimus work?
Inhibitor of mammalian target of rapamycin (mTOR), a serine-threonine kinase; in several cancers and tuberous sclerosis complex, the mTOR pathway is dysregulated; everolimus binds to FKBP-12, an intracellular protein and thus inhibiting the mTOR kinase pathway
What are the common side effects of everolimus?
Asthenia, Constipation, Fatigue, Infection, Cough, Stomatitis, Diarrhea
Which drugs interact with everolimus?
amiodarone, aprepitant, clarithromycin, dronedarone, ketoconazole, measles mumps and rubella vaccine, nilotinib, phenytoin, voriconazole, atorvastatin, chloramphenicol, clotrimazole, dasatinib, efavirenz, erythromycin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.