Drug interactions
Cholera vaccine + Tedizolid
Severity: Moderate
Cholera vaccine and Tedizolid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Live attenuated oral cholera vaccine must replicate in the gut to produce immunity. Antibiotics active against the vaccine strain may reduce its viability and impair immune response.
What this interaction means in plain words
Cholera vaccine and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity may kill the live attenuated vaccine strain, reducing immunogenicity.
What to do
Do not give the live oral cholera vaccine to a patient who has had antibiotics within 14 days, in line with labeling. Delay vaccination until after the antibiotic course.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cholera vaccine and Tedizolid, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Tedizolid
- Bupropion + Tedizolid Major
- Cyproheptadine + Tedizolid Major
- Deferiprone + Tedizolid Major
- Isocarboxazid + Tedizolid Major
- Meperidine + Tedizolid Major
- Methamphetamine + Tedizolid Major
Frequently asked questions
Can I take Cholera vaccine with Tedizolid?
MediHelp rates the interaction as moderate. Cholera vaccine and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live attenuated oral cholera vaccine must replicate in the gut to produce immunity. Antibiotics active against the vaccine strain may reduce its viability and impair immune response.
How serious is the interaction between Cholera vaccine and Tedizolid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live oral cholera vaccine to a patient who has had antibiotics within 14 days, in line with labeling. Delay vaccination until after the antibiotic course.
What other medicines interact with Tedizolid?
MediHelp also lists interactions of Tedizolid with, for example, Bupropion, Cyproheptadine, Deferiprone. The full list is on the Tedizolid page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
