Drug interactions
Deferiprone + Tedizolid
Severity: Major
Deferiprone and Tedizolid: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause bone marrow suppression, and deferiprone carries a boxed warning for agranulocytosis and neutropenia. Combining them could increase the risk of severe neutropenia and infection.
What this interaction means in plain words
Deferiprone and Tedizolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Tedizolid belongs to Anti Bacterial.
Why it happens
Additive myelosuppressive effects of two agents associated with neutropenia.
What to do
Avoid the combination if an alternative antibiotic is possible. If used together, monitor the absolute neutrophil count more frequently than the usual schedule.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Tedizolid
Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Tedizolid?
MediHelp rates the interaction as major. Deferiprone and Tedizolid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can cause bone marrow suppression, and deferiprone carries a boxed warning for agranulocytosis and neutropenia. Combining them could increase the risk of severe neutropenia and infection.
How serious is the interaction between Deferiprone and Tedizolid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if an alternative antibiotic is possible. If used together, monitor the absolute neutrophil count more frequently than the usual schedule.
What other medicines interact with Tedizolid?
MediHelp also lists interactions of Tedizolid with, for example, Bupropion, Cyproheptadine, Isocarboxazid. The full list is on the Tedizolid page.
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