Drug interactions
Cholera vaccine + Temozolomide
Severity: Minor
Cholera vaccine and Temozolomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temozolomide can cause lymphopenia and immunosuppression, which may reduce the response to oral cholera vaccine. Protection may be incomplete in treated patients.
What this interaction means in plain words
Cholera vaccine and Temozolomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Chemotherapy-related immunosuppression impairs the immune response to the vaccine.
What to do
Vaccinate before starting temozolomide if travel is planned, or defer until immune recovery. Emphasize food and water hygiene.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Temozolomide
Frequently asked questions
Can I take Cholera vaccine with Temozolomide?
MediHelp rates the interaction as minor. Cholera vaccine and Temozolomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temozolomide can cause lymphopenia and immunosuppression, which may reduce the response to oral cholera vaccine. Protection may be incomplete in treated patients.
How serious is the interaction between Cholera vaccine and Temozolomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before starting temozolomide if travel is planned, or defer until immune recovery. Emphasize food and water hygiene.
What other medicines interact with Temozolomide?
MediHelp also lists interactions of Temozolomide with, for example, Adenovirus types 4 and 7 live, Belatacept, Deferiprone. The full list is on the Temozolomide page.
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