Drug reference
temozolomide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Alkylating Agents)
Mechanism of action
Imidazotetrazine derivative prodrug; active metabolite MTIC methylates guanine-rich areas of DNA that initiate transcription, which lead to DNA double strand breaks and apoptosis
Common side effects
- Alopecia
- Constipation
- Vomiting
- Headache
- Fatigue
- Nausea
- Lymphopenia
Related conditions
Frequently asked questions
What drug class is temozolomide?
temozolomide belongs to: Oncology.
How does temozolomide work?
Imidazotetrazine derivative prodrug; active metabolite MTIC methylates guanine-rich areas of DNA that initiate transcription, which lead to DNA double strand breaks and apoptosis
What are the common side effects of temozolomide?
Alopecia, Constipation, Vomiting, Headache, Fatigue, Nausea, Lymphopenia
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