Drug interactions
Cholestyramine + Tiratricol
Severity: Moderate
Cholestyramine and Tiratricol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cholestyramine strongly binds thyroid hormone analogues in the intestine and can markedly reduce their absorption. This may cause under-replacement.
What this interaction means in plain words
Cholestyramine and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholestyramine belongs to Cardiovascular; Tiratricol belongs to Endocrine.
Why it happens
Anion-exchange resin binds tiratricol in the gut and also interrupts its enterohepatic circulation.
What to do
Take tiratricol at least 1 hour before or 4 hours after cholestyramine, and monitor T3 levels.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiratricol
- Levothyroxine + Tiratricol Major
- Calcium + Tiratricol Moderate
- Carbamazepine + Tiratricol Moderate
- Carbimazole + Tiratricol Moderate
- Charcoal + Tiratricol Moderate
- Chloroquine + Tiratricol Moderate
Other interactions of Cholestyramine
Frequently asked questions
Can I take Cholestyramine with Tiratricol?
MediHelp rates the interaction as moderate. Cholestyramine and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine strongly binds thyroid hormone analogues in the intestine and can markedly reduce their absorption. This may cause under-replacement.
How serious is the interaction between Cholestyramine and Tiratricol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take tiratricol at least 1 hour before or 4 hours after cholestyramine, and monitor T3 levels.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Levothyroxine, Calcium, Carbamazepine. The full list is on the Tiratricol page.
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