Drug interactions
Chloroquine + Tiratricol
Severity: Moderate
Chloroquine and Tiratricol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloroquine has been associated with hypothyroidism and may blunt the effect of thyroid hormone replacement. The interaction is not well characterized.
What this interaction means in plain words
Chloroquine and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chloroquine belongs to Anti Parasitic; Tiratricol belongs to Endocrine.
Why it happens
The mechanism is not well established; chloroquine may impair thyroid hormone synthesis or action.
What to do
Monitor T3 and thyroid function during co-treatment and adjust the tiratricol dose according to results.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiratricol
- Levothyroxine + Tiratricol Major
- Calcium + Tiratricol Moderate
- Carbamazepine + Tiratricol Moderate
- Carbimazole + Tiratricol Moderate
- Charcoal + Tiratricol Moderate
- Cholestyramine + Tiratricol Moderate
Other interactions of Chloroquine
- Chloroquine + Cisapride Contraindicated
- Chloroquine + Dofetilide Contraindicated
- Chloroquine + Dronedarone Contraindicated
- Chloroquine + Droperidol Contraindicated
- Chloroquine + Panobinostat Contraindicated
- Chloroquine + Pimozide Contraindicated
Frequently asked questions
Can I take Chloroquine with Tiratricol?
MediHelp rates the interaction as moderate. Chloroquine and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chloroquine has been associated with hypothyroidism and may blunt the effect of thyroid hormone replacement. The interaction is not well characterized.
How serious is the interaction between Chloroquine and Tiratricol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor T3 and thyroid function during co-treatment and adjust the tiratricol dose according to results.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Levothyroxine, Calcium, Carbamazepine. The full list is on the Tiratricol page.
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