Drug interactions
Choline magnesium trisalicylate + Penicillin g
Severity: Minor
Choline magnesium trisalicylate and Penicillin g: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salicylates compete with penicillin G for renal tubular secretion and protein binding, which can raise penicillin concentrations. The effect is usually modest and mostly relevant at high doses.
What this interaction means in plain words
Choline magnesium trisalicylate and Penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal tubular organic anion secretion and plasma protein binding sites.
What to do
No routine change is needed; monitor for penicillin toxicity with high doses or renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Penicillin g
- Amifampridine + Penicillin g Moderate
- Amiloride + Penicillin g Moderate
- Bcg vaccine live + Penicillin g Moderate
- Cholera vaccine + Penicillin g Moderate
- Colestipol + Penicillin g Moderate
- Deflazacort + Penicillin g Moderate
Frequently asked questions
Can I take Choline magnesium trisalicylate with Penicillin g?
MediHelp rates the interaction as minor. Choline magnesium trisalicylate and Penicillin g have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Salicylates compete with penicillin G for renal tubular secretion and protein binding, which can raise penicillin concentrations. The effect is usually modest and mostly relevant at high doses.
How serious is the interaction between Choline magnesium trisalicylate and Penicillin g?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for penicillin toxicity with high doses or renal impairment.
What other medicines interact with Penicillin g?
MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.
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