Drug interactions
Ciprofloxacin + Fluticasone-vilanterol
Severity: Moderate
Ciprofloxacin and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ciprofloxacin has a small QT-prolonging effect, and vilanterol may add tachycardia and hypokalemia. The combined risk is usually low but matters in patients with other QT risk factors.
What this interaction means in plain words
Ciprofloxacin and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-2 agonist-related hypokalemia.
What to do
Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Consider an alternative antibiotic if risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Frequently asked questions
Can I take Ciprofloxacin with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Ciprofloxacin and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ciprofloxacin has a small QT-prolonging effect, and vilanterol may add tachycardia and hypokalemia. The combined risk is usually low but matters in patients with other QT risk factors.
How serious is the interaction between Ciprofloxacin and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with cardiac disease or other QT-prolonging drugs. Consider an alternative antibiotic if risk is high.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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