Drug interactions
Ciprofloxacin + Formoterol-mometasone
Severity: Minor
Ciprofloxacin and Formoterol-mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones and corticosteroids together increase the risk of tendinopathy and tendon rupture, mainly with systemic corticosteroids and in older patients. With inhaled mometasone the systemic exposure is low, so the added risk is small. Ciprofloxacin can also prolong QT, which may add to formoterol effects.
What this interaction means in plain words
Ciprofloxacin and Formoterol-mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive tendon toxicity from fluoroquinolone and corticosteroid exposure, with minimal systemic steroid exposure from inhalation.
What to do
Counsel patients to stop ciprofloxacin and seek review if tendon pain or swelling develops. Take extra care in older patients or those also on systemic corticosteroids.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol-mometasone
Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Frequently asked questions
Can I take Ciprofloxacin with Formoterol-mometasone?
MediHelp rates the interaction as minor. Ciprofloxacin and Formoterol-mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones and corticosteroids together increase the risk of tendinopathy and tendon rupture, mainly with systemic corticosteroids and in older patients. With inhaled mometasone the systemic exposure is low, so the added risk is small. Ciprofloxacin can also prolong QT, which may add to formoterol effects.
How serious is the interaction between Ciprofloxacin and Formoterol-mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to stop ciprofloxacin and seek review if tendon pain or swelling develops. Take extra care in older patients or those also on systemic corticosteroids.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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