Drug interactions
Ciprofloxacin + Tetrabenazine
Severity: Moderate
Ciprofloxacin and Tetrabenazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetrabenazine can prolong the QT interval modestly, and ciprofloxacin may add to this effect. The combination may increase torsades risk in susceptible patients.
What this interaction means in plain words
Ciprofloxacin and Tetrabenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Tetrabenazine belongs to Central Nervous System.
Why it happens
Additive prolongation of cardiac repolarization.
What to do
Monitor ECG in patients with other QT risk factors and correct electrolytes. Consider an alternative antibiotic in patients with congenital long QT or heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Tetrabenazine
- Dronedarone + Tetrabenazine Contraindicated
- Isocarboxazid + Tetrabenazine Contraindicated
- Linezolid + Tetrabenazine Contraindicated
- Phenelzine + Tetrabenazine Contraindicated
- Pimozide + Tetrabenazine Contraindicated
- Procarbazine + Tetrabenazine Contraindicated
Frequently asked questions
Can I take Ciprofloxacin with Tetrabenazine?
MediHelp rates the interaction as moderate. Ciprofloxacin and Tetrabenazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetrabenazine can prolong the QT interval modestly, and ciprofloxacin may add to this effect. The combination may increase torsades risk in susceptible patients.
How serious is the interaction between Ciprofloxacin and Tetrabenazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with other QT risk factors and correct electrolytes. Consider an alternative antibiotic in patients with congenital long QT or heart disease.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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