Drug interactions
ciprofloxacin + warfarin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ INR/bleeding risk (variable).
Mechanism of action
CYP inhibition/disruption of gut flora.
Clinical management
Monitor INR closely; adjust dose as needed.
Drug reference
References
Frequently asked questions
Can I take ciprofloxacin with warfarin?
The interaction is rated: Major. ↑ INR/bleeding risk (variable).
How serious is the interaction between ciprofloxacin and warfarin?
The interaction is rated: Major. Evidence level: Moderate.
How is the interaction between ciprofloxacin and warfarin managed?
Monitor INR closely; adjust dose as needed.
Why do ciprofloxacin and warfarin interact?
CYP inhibition/disruption of gut flora.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.