Drug interactions
Cisatracurium + Sarecycline
Severity: Minor
Cisatracurium and Sarecycline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracycline-class antibiotics have been reported rarely to potentiate neuromuscular blockers. Sarecycline is an oral acne agent with low systemic exposure, so a clinically relevant effect on cisatracurium is unlikely and not established.
What this interaction means in plain words
Cisatracurium and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cisatracurium belongs to Musculoskeletal; Sarecycline belongs to Anti Bacterial.
Why it happens
Possible weak additive neuromuscular effect typical of tetracyclines; not established for sarecycline.
What to do
No change is generally needed; standard neuromuscular monitoring with train-of-four during anesthesia is sufficient.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisatracurium
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Cisatracurium with Sarecycline?
MediHelp rates the interaction as minor. Cisatracurium and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetracycline-class antibiotics have been reported rarely to potentiate neuromuscular blockers. Sarecycline is an oral acne agent with low systemic exposure, so a clinically relevant effect on cisatracurium is unlikely and not established.
How serious is the interaction between Cisatracurium and Sarecycline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is generally needed; standard neuromuscular monitoring with train-of-four during anesthesia is sufficient.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
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