Drug interactions
Cisplatin + Etrasimod
Severity: Moderate
Cisplatin and Etrasimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod lowers circulating lymphocytes and cisplatin is myelosuppressive. Together they may add to immunosuppression and infection risk, and the combination has not been formally studied.
What this interaction means in plain words
Cisplatin and Etrasimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cisplatin belongs to Oncology; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Additive pharmacodynamic immunosuppression through lymphocyte sequestration and cytotoxic marrow suppression.
What to do
Avoid the combination where possible. If both are needed, monitor complete blood count with lymphocytes and watch for infections.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cisplatin
- Cidofovir + Cisplatin Contraindicated
- Adefovir + Cisplatin Major
- Adenovirus types 4 and 7 live + Cisplatin Major
- Amikacin + Cisplatin Major
- Amphotericin b deoxycholate + Cisplatin Major
- Amphotericin b + Cisplatin Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Cisplatin with Etrasimod?
MediHelp rates the interaction as moderate. Cisplatin and Etrasimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etrasimod lowers circulating lymphocytes and cisplatin is myelosuppressive. Together they may add to immunosuppression and infection risk, and the combination has not been formally studied.
How serious is the interaction between Cisplatin and Etrasimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If both are needed, monitor complete blood count with lymphocytes and watch for infections.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Adenovirus types 4 and 7 live. The full list is on the Cisplatin page.
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