Drug interactions
Citalopram + Tedizolid
Severity: Moderate
Citalopram and Tedizolid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tedizolid weakly and reversibly inhibits MAO, and citalopram is an SSRI. Serotonin syndrome is theoretically possible, but tedizolid has shown low serotonergic liability clinically.
What this interaction means in plain words
Citalopram and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Citalopram belongs to Central Nervous System; Tedizolid belongs to Anti Bacterial.
Why it happens
Theoretical additive serotonergic effect from weak MAO inhibition plus serotonin reuptake inhibition.
What to do
The combination can be used if needed; monitor for symptoms of serotonin toxicity and counsel the patient to report agitation, tremor or fever.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tedizolid
- Bupropion + Tedizolid Major
- Cyproheptadine + Tedizolid Major
- Deferiprone + Tedizolid Major
- Isocarboxazid + Tedizolid Major
- Meperidine + Tedizolid Major
- Methamphetamine + Tedizolid Major
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Tedizolid?
MediHelp rates the interaction as moderate. Citalopram and Tedizolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tedizolid weakly and reversibly inhibits MAO, and citalopram is an SSRI. Serotonin syndrome is theoretically possible, but tedizolid has shown low serotonergic liability clinically.
How serious is the interaction between Citalopram and Tedizolid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: The combination can be used if needed; monitor for symptoms of serotonin toxicity and counsel the patient to report agitation, tremor or fever.
What other medicines interact with Tedizolid?
MediHelp also lists interactions of Tedizolid with, for example, Bupropion, Cyproheptadine, Deferiprone. The full list is on the Tedizolid page.
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