Drug interactions
Citalopram + Triclabendazole
Severity: Moderate
Citalopram and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole can prolong the QT interval and may inhibit CYP2C19, raising citalopram levels. Together these effects increase the risk of arrhythmia, although the treatment course is short.
What this interaction means in plain words
Citalopram and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Citalopram belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT prolongation plus possible CYP2C19 inhibition that raises citalopram exposure.
What to do
Obtain an ECG and correct electrolytes before treatment in patients with other QT risk factors. Consider temporarily holding or reducing citalopram when risk is high.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Citalopram with Triclabendazole?
MediHelp rates the interaction as moderate. Citalopram and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong the QT interval and may inhibit CYP2C19, raising citalopram levels. Together these effects increase the risk of arrhythmia, although the treatment course is short.
How serious is the interaction between Citalopram and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and correct electrolytes before treatment in patients with other QT risk factors. Consider temporarily holding or reducing citalopram when risk is high.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.
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