Drug interactions
Clemastine + Propylhexedrine
Severity: Minor
Clemastine and Propylhexedrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a volatile sympathomimetic decongestant with mild stimulant effects that may slightly offset clemastine sedation. No significant adverse interaction is established.
What this interaction means in plain words
Clemastine and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clemastine belongs to Respiratory; Propylhexedrine belongs to Respiratory.
Why it happens
Opposing pharmacodynamic effects on CNS arousal; no established pharmacokinetic mechanism.
What to do
No specific action is needed; counsel the patient that clemastine drowsiness may persist.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clemastine
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Clemastine with Propylhexedrine?
MediHelp rates the interaction as minor. Clemastine and Propylhexedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propylhexedrine is a volatile sympathomimetic decongestant with mild stimulant effects that may slightly offset clemastine sedation. No significant adverse interaction is established.
How serious is the interaction between Clemastine and Propylhexedrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; counsel the patient that clemastine drowsiness may persist.
What other medicines interact with Clemastine?
MediHelp also lists interactions of Clemastine with, for example, Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal. The full list is on the Clemastine page.
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