Drug interactions
Clobazam + Ropinirole
Severity: Moderate
Clobazam and Ropinirole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs cause CNS depression, so together they may increase drowsiness, dizziness and impaired coordination. Respiratory depression is uncommon but possible in vulnerable patients.
What this interaction means in plain words
Clobazam and Ropinirole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clobazam belongs to Central Nervous System; Ropinirole belongs to Central Nervous System.
Why it happens
Additive CNS depressant pharmacodynamic effects.
What to do
Start at low doses, monitor sedation and counsel on driving and machinery. Reduce doses if excessive sedation appears.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Clobazam and Ropinirole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ropinirole
- Amisulpride + Ropinirole Contraindicated
- Chlorpromazine + Ropinirole Major
- Droperidol + Ropinirole Major
- Fluphenazine + Ropinirole Major
- Fluvoxamine + Ropinirole Major
- Haloperidol + Ropinirole Major
Other interactions of Clobazam
- Amobarbital + Clobazam Major
- Buprenorphine + Clobazam Major
- Butorphanol + Clobazam Major
- Carisoprodol + Clobazam Major
- Chloral hydrate + Clobazam Major
- Clobazam + Clozapine Major
Frequently asked questions
Can I take Clobazam with Ropinirole?
MediHelp rates the interaction as moderate. Clobazam and Ropinirole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause CNS depression, so together they may increase drowsiness, dizziness and impaired coordination. Respiratory depression is uncommon but possible in vulnerable patients.
How serious is the interaction between Clobazam and Ropinirole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start at low doses, monitor sedation and counsel on driving and machinery. Reduce doses if excessive sedation appears.
What other medicines interact with Ropinirole?
MediHelp also lists interactions of Ropinirole with, for example, Amisulpride, Chlorpromazine, Droperidol. The full list is on the Ropinirole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
