Drug interactions
Colestipol + Rosuvastatin
Severity: Minor
Colestipol and Rosuvastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colestipol may reduce rosuvastatin absorption, though the combination still lowers LDL cholesterol additively. The effect is of limited clinical concern if doses are separated.
What this interaction means in plain words
Colestipol and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Colestipol belongs to Cardiovascular; Rosuvastatin belongs to Cardiovascular.
Why it happens
Bile acid sequestrant binds rosuvastatin in the gut, reducing absorption.
What to do
Give rosuvastatin at least 2 hours before colestipol, and monitor lipid response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosuvastatin
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Rosuvastatin?
MediHelp rates the interaction as minor. Colestipol and Rosuvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Colestipol may reduce rosuvastatin absorption, though the combination still lowers LDL cholesterol additively. The effect is of limited clinical concern if doses are separated.
How serious is the interaction between Colestipol and Rosuvastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give rosuvastatin at least 2 hours before colestipol, and monitor lipid response.
What other medicines interact with Rosuvastatin?
MediHelp also lists interactions of Rosuvastatin with, for example, Atazanavir, Cyclosporin, Darolutamide. The full list is on the Rosuvastatin page.
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