Drug interactions
Colistin + Teicoplanin
Severity: Moderate
Colistin and Teicoplanin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colistin is nephrotoxic, and teicoplanin can also cause kidney injury, although less often than vancomycin. Combined use may increase the risk of renal impairment.
What this interaction means in plain words
Colistin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colistin belongs to Anti Bacterial; Teicoplanin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxic effects on the renal tubule.
What to do
Monitor serum creatinine and urine output regularly during co-therapy. Adjust doses to renal function and measure teicoplanin trough levels where available.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Colistin and Teicoplanin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Colistin
- Colistin + Polymyxin b Contraindicated
- Amikacin + Colistin Major
- Amphotericin b deoxycholate + Colistin Major
- Amphotericin b + Colistin Major
- Atracurium + Colistin Major
- Bacitracin + Colistin Major
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Colistin with Teicoplanin?
MediHelp rates the interaction as moderate. Colistin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colistin is nephrotoxic, and teicoplanin can also cause kidney injury, although less often than vancomycin. Combined use may increase the risk of renal impairment.
How serious is the interaction between Colistin and Teicoplanin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output regularly during co-therapy. Adjust doses to renal function and measure teicoplanin trough levels where available.
What other medicines interact with Colistin?
MediHelp also lists interactions of Colistin with, for example, Polymyxin b, Amikacin, Amphotericin b deoxycholate. The full list is on the Colistin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
