Drug interactions
Conivaptan + Finasteride
Severity: Minor
Conivaptan and Finasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Conivaptan is a CYP3A4 inhibitor and may increase finasteride exposure. Because of finasteride's wide safety margin and the short hospital use of conivaptan, clinical effects are unlikely.
What this interaction means in plain words
Conivaptan and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4-mediated finasteride metabolism.
What to do
No dose adjustment is needed during short-term conivaptan therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Frequently asked questions
Can I take Conivaptan with Finasteride?
MediHelp rates the interaction as minor. Conivaptan and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Conivaptan is a CYP3A4 inhibitor and may increase finasteride exposure. Because of finasteride's wide safety margin and the short hospital use of conivaptan, clinical effects are unlikely.
How serious is the interaction between Conivaptan and Finasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed during short-term conivaptan therapy.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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