Drug interactions
Aprepitant + Finasteride
Severity: Minor
Aprepitant and Finasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Finasteride is metabolised by CYP3A4, so aprepitant may modestly raise its levels. Finasteride is well tolerated across a wide exposure range, so clinical effects are unlikely.
What this interaction means in plain words
Aprepitant and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aprepitant belongs to Gastrointestinal Tract; Finasteride belongs to Genitourinary.
Why it happens
Aprepitant inhibits CYP3A4, reducing finasteride clearance.
What to do
No dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aprepitant
- Aprepitant + Lomitapide Contraindicated
- Aprepitant + Pimozide Contraindicated
- Aprepitant + Avapritinib Major
- Aprepitant + Bosutinib Major
- Aprepitant + Carbamazepine Major
- Aprepitant + Cobicistat Major
Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Armodafinil + Finasteride Minor
Frequently asked questions
Can I take Aprepitant with Finasteride?
MediHelp rates the interaction as minor. Aprepitant and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Finasteride is metabolised by CYP3A4, so aprepitant may modestly raise its levels. Finasteride is well tolerated across a wide exposure range, so clinical effects are unlikely.
How serious is the interaction between Aprepitant and Finasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed.
What other medicines interact with Aprepitant?
MediHelp also lists interactions of Aprepitant with, for example, Lomitapide, Pimozide, Avapritinib. The full list is on the Aprepitant page.
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