Drug interactions
Corticorelin + Mometasone
Severity: Minor
Corticorelin and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids suppress the hypothalamic-pituitary-adrenal axis and can blunt the ACTH response to corticorelin. This may lead to misinterpretation of the diagnostic test, though inhaled mometasone has a smaller effect than systemic steroids.
What this interaction means in plain words
Corticorelin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoid negative feedback suppresses pituitary corticotroph responsiveness to corticorelin.
What to do
Interpret corticorelin test results in light of corticosteroid use, and consider timing the test to account for steroid exposure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Frequently asked questions
Can I take Corticorelin with Mometasone?
MediHelp rates the interaction as minor. Corticorelin and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids suppress the hypothalamic-pituitary-adrenal axis and can blunt the ACTH response to corticorelin. This may lead to misinterpretation of the diagnostic test, though inhaled mometasone has a smaller effect than systemic steroids.
How serious is the interaction between Corticorelin and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret corticorelin test results in light of corticosteroid use, and consider timing the test to account for steroid exposure.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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