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Drug interactions

Cortisone + Ergotamine

Severity: Minor

Cortisone and Ergotamine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Corticosteroids are weak CYP3A4 inducers, and any reduction in ergotamine levels is likely small. Clinical significance is minimal.

What this interaction means in plain words

Cortisone and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Weak induction of CYP3A4 may slightly increase ergotamine metabolism.

What to do

No specific action needed; monitor migraine response.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cortisone with Ergotamine?

MediHelp rates the interaction as minor. Cortisone and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids are weak CYP3A4 inducers, and any reduction in ergotamine levels is likely small. Clinical significance is minimal.

How serious is the interaction between Cortisone and Ergotamine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action needed; monitor migraine response.

What other medicines interact with Ergotamine?

MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.

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