Drug interactions
clarithromycin + ergotamine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Severe vasospasm/ischemia risk; contraindicated.
Mechanism of action
Strong CYP3A4 inhibition.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take clarithromycin with ergotamine?
The interaction is rated: Contraindicated. Severe vasospasm/ischemia risk; contraindicated.
How serious is the interaction between clarithromycin and ergotamine?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between clarithromycin and ergotamine managed?
Contraindicated.
Why do clarithromycin and ergotamine interact?
Strong CYP3A4 inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.