Drug interactions
Cortisone + Indacaterol
Severity: Moderate
Cortisone and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids such as cortisone cause renal potassium loss through mineralocorticoid activity, and beta-2 agonists shift potassium into cells. Combining them may result in additive hypokalemia, which can predispose to arrhythmia.
What this interaction means in plain words
Cortisone and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from mineralocorticoid-mediated potassium wasting and beta-2-mediated cellular uptake.
What to do
Monitor serum potassium in patients on prolonged or high-dose cortisone, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cortisone and Indacaterol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indacaterol
Frequently asked questions
Can I take Cortisone with Indacaterol?
MediHelp rates the interaction as moderate. Cortisone and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids such as cortisone cause renal potassium loss through mineralocorticoid activity, and beta-2 agonists shift potassium into cells. Combining them may result in additive hypokalemia, which can predispose to arrhythmia.
How serious is the interaction between Cortisone and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on prolonged or high-dose cortisone, and replace potassium as needed.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
