Drug interactions
Crofelemer + Pitavastatin
Severity: Minor
Crofelemer and Pitavastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Crofelemer is minimally absorbed but may inhibit gut transporters. A meaningful change in pitavastatin exposure is unlikely, and no clear clinical interaction has been shown.
What this interaction means in plain words
Crofelemer and Pitavastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Crofelemer belongs to Gastrointestinal Tract; Pitavastatin belongs to Cardiovascular.
Why it happens
Crofelemer may inhibit intestinal transporters such as OATP1A2 and MRP2, but systemic effects are not established.
What to do
No action is needed beyond awareness. Monitor for muscle symptoms if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pitavastatin
Other interactions of Crofelemer
- Crofelemer + Ergotamine Moderate
- Alfuzosin + Crofelemer Minor
- Amiodarone + Crofelemer Minor
- Apixaban + Crofelemer Minor
- Aprepitant + Crofelemer Minor
- Armodafinil + Crofelemer Minor
Frequently asked questions
Can I take Crofelemer with Pitavastatin?
MediHelp rates the interaction as minor. Crofelemer and Pitavastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Crofelemer is minimally absorbed but may inhibit gut transporters. A meaningful change in pitavastatin exposure is unlikely, and no clear clinical interaction has been shown.
How serious is the interaction between Crofelemer and Pitavastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed beyond awareness. Monitor for muscle symptoms if they occur.
What other medicines interact with Pitavastatin?
MediHelp also lists interactions of Pitavastatin with, for example, Cyclosporin, Erythromycin base, Erythromycin ethylsuccinate. The full list is on the Pitavastatin page.
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