Drug interactions
Dalteparin + Fish oil
Severity: Minor
Dalteparin and Fish oil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omega-3 fatty acids at higher doses mildly reduce platelet aggregation. Together with dalteparin this might slightly increase bleeding, although clinically significant bleeding has not been consistently shown.
What this interaction means in plain words
Dalteparin and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dalteparin belongs to Cardiovascular; Fish oil belongs to Gastrointestinal Tract.
Why it happens
Omega-3 fatty acids modestly inhibit platelet function, which may add to dalteparin anticoagulation.
What to do
No dose change is usually required; watch for bruising or bleeding when high doses of fish oil are taken. Reassess the need for supplements before surgery or procedures.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Other interactions of Fish oil
- Antithrombin alfa + Fish oil Moderate
- Antithrombin iii + Fish oil Moderate
- Aspirin / citric acid / sodium bicarbonate + Fish oil Moderate
- Aspirin + Fish oil Moderate
- Betrixaban + Fish oil Moderate
- Bivalirudin + Fish oil Moderate
Frequently asked questions
Can I take Dalteparin with Fish oil?
MediHelp rates the interaction as minor. Dalteparin and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids at higher doses mildly reduce platelet aggregation. Together with dalteparin this might slightly increase bleeding, although clinically significant bleeding has not been consistently shown.
How serious is the interaction between Dalteparin and Fish oil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually required; watch for bruising or bleeding when high doses of fish oil are taken. Reassess the need for supplements before surgery or procedures.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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