Drug interactions
Dalteparin + Moexipril
Severity: Moderate
Dalteparin and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heparins, including low molecular weight heparins, can suppress aldosterone production and cause hyperkalemia. With an ACE inhibitor, which also reduces aldosterone, the risk of raised potassium increases, especially in renal impairment or diabetes.
What this interaction means in plain words
Dalteparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dalteparin belongs to Cardiovascular; Moexipril belongs to Cardiovascular.
Why it happens
Heparin inhibits adrenal aldosterone synthesis, adding to the reduced aldosterone effect from ACE inhibition.
What to do
Check serum potassium before and during prolonged dalteparin use with an ACE inhibitor, particularly in patients with renal impairment or diabetes. Treat hyperkalemia if it develops and review the need for either drug.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Moexipril?
MediHelp rates the interaction as moderate. Dalteparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heparins, including low molecular weight heparins, can suppress aldosterone production and cause hyperkalemia. With an ACE inhibitor, which also reduces aldosterone, the risk of raised potassium increases, especially in renal impairment or diabetes.
How serious is the interaction between Dalteparin and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium before and during prolonged dalteparin use with an ACE inhibitor, particularly in patients with renal impairment or diabetes. Treat hyperkalemia if it develops and review the need for either drug.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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