Drug interactions
Dalteparin + Quinine
Severity: Moderate
Dalteparin and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine can rarely cause thrombocytopenia and has been reported to affect hemostasis, which may add to the bleeding risk of dalteparin. The magnitude of any interaction is uncertain.
What this interaction means in plain words
Dalteparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dalteparin belongs to Cardiovascular; Quinine belongs to Anti Parasitic.
Why it happens
Mechanism is not established; possible additive bleeding risk through quinine-induced thrombocytopenia.
What to do
Monitor platelet counts and watch for bleeding. Stop quinine if unexplained thrombocytopenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Quinine?
MediHelp rates the interaction as moderate. Dalteparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine can rarely cause thrombocytopenia and has been reported to affect hemostasis, which may add to the bleeding risk of dalteparin. The magnitude of any interaction is uncertain.
How serious is the interaction between Dalteparin and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor platelet counts and watch for bleeding. Stop quinine if unexplained thrombocytopenia develops.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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