Drug interactions
Danazol + Esomeprazole
Severity: Minor
Danazol and Esomeprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol inhibits CYP3A4 and could raise esomeprazole levels slightly. Since CYP2C19 is the main pathway, the effect is small.
What this interaction means in plain words
Danazol and Esomeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Danazol inhibits CYP3A4, a secondary pathway for esomeprazole metabolism.
What to do
No dose change is usually needed; monitor for esomeprazole adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esomeprazole
- Esomeprazole + Mavacamten Contraindicated
- Esomeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Esomeprazole Major
- Atazanavir + Esomeprazole Major
- Citalopram + Esomeprazole Major
- Clopidogrel + Esomeprazole Major
Frequently asked questions
Can I take Danazol with Esomeprazole?
MediHelp rates the interaction as minor. Danazol and Esomeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol inhibits CYP3A4 and could raise esomeprazole levels slightly. Since CYP2C19 is the main pathway, the effect is small.
How serious is the interaction between Danazol and Esomeprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for esomeprazole adverse effects.
What other medicines interact with Esomeprazole?
MediHelp also lists interactions of Esomeprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Esomeprazole page.
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