Drug interactions
Danazol + Ixazomib
Severity: Minor
Danazol and Ixazomib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol is a weak-to-moderate CYP3A4 inhibitor and could slightly raise ixazomib levels. Because ixazomib exposure is little affected even by strong CYP3A inhibitors, the interaction is unlikely to be significant.
What this interaction means in plain words
Danazol and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Danazol inhibits CYP3A4, which may slightly reduce ixazomib metabolism.
What to do
No dose change is needed; monitor for ixazomib toxicity.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ixazomib
- Apalutamide + Ixazomib Major
- Carbamazepine + Ixazomib Major
- Dabrafenib + Ixazomib Major
- Enzalutamide + Ixazomib Major
- Etrasimod + Ixazomib Major
- Fosphenytoin + Ixazomib Major
Frequently asked questions
Can I take Danazol with Ixazomib?
MediHelp rates the interaction as minor. Danazol and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol is a weak-to-moderate CYP3A4 inhibitor and could slightly raise ixazomib levels. Because ixazomib exposure is little affected even by strong CYP3A inhibitors, the interaction is unlikely to be significant.
How serious is the interaction between Danazol and Ixazomib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor for ixazomib toxicity.
What other medicines interact with Ixazomib?
MediHelp also lists interactions of Ixazomib with, for example, Apalutamide, Carbamazepine, Dabrafenib. The full list is on the Ixazomib page.
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