Drug interactions
Danicopan + Empagliflozin-linagliptin
Severity: Minor
Danicopan and Empagliflozin-linagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danicopan inhibits P-gp and may increase linagliptin concentrations. Linagliptin has a wide therapeutic margin, so a clinically significant effect is unlikely.
What this interaction means in plain words
Danicopan and Empagliflozin-linagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Danicopan belongs to Miscellaneous; Empagliflozin-linagliptin belongs to Endocrine.
Why it happens
P-gp inhibition decreases linagliptin efflux.
What to do
No dose change is needed; monitor for linagliptin adverse effects such as hypoglycemia if used with other agents.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-linagliptin
Other interactions of Danicopan
- Amiodarone + Danicopan Moderate
- Apixaban + Danicopan Moderate
- Atorvastatin + Danicopan Moderate
- Brentuximab + Danicopan Moderate
- Carvedilol + Danicopan Moderate
- Cladribine + Danicopan Moderate
Frequently asked questions
Can I take Danicopan with Empagliflozin-linagliptin?
MediHelp rates the interaction as minor. Danicopan and Empagliflozin-linagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danicopan inhibits P-gp and may increase linagliptin concentrations. Linagliptin has a wide therapeutic margin, so a clinically significant effect is unlikely.
How serious is the interaction between Danicopan and Empagliflozin-linagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor for linagliptin adverse effects such as hypoglycemia if used with other agents.
What other medicines interact with Empagliflozin-linagliptin?
MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.
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