Drug interactions
Darifenacin + Finasteride
Severity: Minor
Darifenacin and Finasteride: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Darifenacin is a weak-to-moderate CYP3A4 inhibitor and could slightly raise finasteride levels. Finasteride is well tolerated across a wide exposure range, so this is unlikely to matter clinically.
What this interaction means in plain words
Darifenacin and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Darifenacin belongs to Genitourinary; Finasteride belongs to Genitourinary.
Why it happens
Inhibition of CYP3A4-mediated finasteride metabolism.
What to do
No dose adjustment is required. Routine monitoring for finasteride adverse effects is sufficient.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Darifenacin
Frequently asked questions
Can I take Darifenacin with Finasteride?
MediHelp rates the interaction as minor. Darifenacin and Finasteride have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Darifenacin is a weak-to-moderate CYP3A4 inhibitor and could slightly raise finasteride levels. Finasteride is well tolerated across a wide exposure range, so this is unlikely to matter clinically.
How serious is the interaction between Darifenacin and Finasteride?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required. Routine monitoring for finasteride adverse effects is sufficient.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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