Drug interactions
Dasatinib + Galantamine
Severity: Minor
Dasatinib and Galantamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is a weak time-dependent CYP3A4 inhibitor and could modestly raise galantamine levels. This may increase cholinergic adverse effects such as nausea, vomiting and bradycardia, though the effect is likely small.
What this interaction means in plain words
Dasatinib and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasatinib belongs to Oncology; Galantamine belongs to Central Nervous System.
Why it happens
Weak CYP3A4 inhibition by dasatinib reduces galantamine metabolism.
What to do
Monitor for nausea, vomiting and slow heart rate after dasatinib is started. Lower the galantamine dose if cholinergic effects develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Galantamine?
MediHelp rates the interaction as minor. Dasatinib and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib is a weak time-dependent CYP3A4 inhibitor and could modestly raise galantamine levels. This may increase cholinergic adverse effects such as nausea, vomiting and bradycardia, though the effect is likely small.
How serious is the interaction between Dasatinib and Galantamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for nausea, vomiting and slow heart rate after dasatinib is started. Lower the galantamine dose if cholinergic effects develop.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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