Drug interactions
Dasatinib + Salbutamol
Severity: Minor
Dasatinib and Salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib can prolong the QT interval, and salbutamol may add to this effect and lower potassium, particularly at high or systemic doses. The combined risk of arrhythmia is modest but relevant in patients with other risk factors.
What this interaction means in plain words
Dasatinib and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasatinib belongs to Oncology; Salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-2 agonist-induced hypokalemia as a contributing factor.
What to do
Obtain baseline ECG and correct potassium and magnesium before regular or high-dose salbutamol use with dasatinib. Repeat ECG if symptoms or additional QT-prolonging drugs are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salbutamol
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Salbutamol?
MediHelp rates the interaction as minor. Dasatinib and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib can prolong the QT interval, and salbutamol may add to this effect and lower potassium, particularly at high or systemic doses. The combined risk of arrhythmia is modest but relevant in patients with other risk factors.
How serious is the interaction between Dasatinib and Salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline ECG and correct potassium and magnesium before regular or high-dose salbutamol use with dasatinib. Repeat ECG if symptoms or additional QT-prolonging drugs are present.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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