Drug interactions
Dasatinib + Triamcinolone
Severity: Minor
Dasatinib and Triamcinolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is a weak time-dependent CYP3A4 inhibitor and may slightly increase triamcinolone exposure. The effect is likely small, though steroid-related adverse effects could increase with repeated dosing. Both drugs can also cause fluid retention.
What this interaction means in plain words
Dasatinib and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasatinib belongs to Oncology; Triamcinolone belongs to Endocrine.
Why it happens
Weak inhibition of CYP3A4 by dasatinib reduces triamcinolone clearance.
What to do
Monitor for fluid retention, hyperglycemia and other signs of steroid excess during prolonged or repeated use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Triamcinolone?
MediHelp rates the interaction as minor. Dasatinib and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib is a weak time-dependent CYP3A4 inhibitor and may slightly increase triamcinolone exposure. The effect is likely small, though steroid-related adverse effects could increase with repeated dosing. Both drugs can also cause fluid retention.
How serious is the interaction between Dasatinib and Triamcinolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for fluid retention, hyperglycemia and other signs of steroid excess during prolonged or repeated use.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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