Drug interactions
Deferasirox + Ergotamine
Severity: Minor
Deferasirox and Ergotamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox has mixed effects on CYP3A4 and may lower ergotamine levels through induction. The effect is uncertain and the clinical impact is probably a reduction in efficacy.
What this interaction means in plain words
Deferasirox and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Ergotamine belongs to Central Nervous System.
Why it happens
Possible CYP3A4 induction by deferasirox increasing ergotamine metabolism; not firmly established.
What to do
No dose change is routinely needed; reassess migraine response and avoid escalating ergotamine beyond labeled limits.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ergotamine
- Almotriptan + Ergotamine Contraindicated
- Atazanavir + Ergotamine Contraindicated
- Clarithromycin + Ergotamine Contraindicated
- Cobicistat + Ergotamine Contraindicated
- Darunavir + Ergotamine Contraindicated
- Dihydroergotamine intranasal + Ergotamine Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Ergotamine?
MediHelp rates the interaction as minor. Deferasirox and Ergotamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox has mixed effects on CYP3A4 and may lower ergotamine levels through induction. The effect is uncertain and the clinical impact is probably a reduction in efficacy.
How serious is the interaction between Deferasirox and Ergotamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is routinely needed; reassess migraine response and avoid escalating ergotamine beyond labeled limits.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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