Drug interactions
Deferasirox + Ferric maltol
Severity: Moderate
Deferasirox and Ferric maltol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox binds iron and opposes the purpose of oral iron replacement. Giving both together makes little sense, as the iron is chelated and iron supplementation counteracts chelation therapy.
What this interaction means in plain words
Deferasirox and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Ferric maltol belongs to Miscellaneous.
Why it happens
Deferasirox chelates iron in the gut, reducing its absorption.
What to do
Avoid combining in iron-overloaded patients; if iron deficiency is documented, reassess the need for chelation before giving iron.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deferasirox
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Deferasirox with Ferric maltol?
MediHelp rates the interaction as moderate. Deferasirox and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox binds iron and opposes the purpose of oral iron replacement. Giving both together makes little sense, as the iron is chelated and iron supplementation counteracts chelation therapy.
How serious is the interaction between Deferasirox and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining in iron-overloaded patients; if iron deficiency is documented, reassess the need for chelation before giving iron.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
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