Drug interactions
Calcium carbonate + Ferric maltol
Severity: Moderate
Calcium carbonate and Ferric maltol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ferric maltol absorption may be reduced by calcium carbonate through higher gastric pH and cation interaction. This may lessen the correction of iron deficiency.
What this interaction means in plain words
Calcium carbonate and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Ferric maltol belongs to Miscellaneous.
Why it happens
Increased gastric pH and calcium competition reduce iron solubility and absorption.
What to do
Take ferric maltol on an empty stomach and separate it from calcium carbonate by at least 2 hours. Monitor hemoglobin and iron indices.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium carbonate
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
- Ciprofloxacin + Ferric maltol Moderate
Frequently asked questions
Can I take Calcium carbonate with Ferric maltol?
MediHelp rates the interaction as moderate. Calcium carbonate and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ferric maltol absorption may be reduced by calcium carbonate through higher gastric pH and cation interaction. This may lessen the correction of iron deficiency.
How serious is the interaction between Calcium carbonate and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take ferric maltol on an empty stomach and separate it from calcium carbonate by at least 2 hours. Monitor hemoglobin and iron indices.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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