Drug interactions
Calcium + Ferric maltol
Severity: Moderate
Calcium and Ferric maltol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium salts may reduce the absorption of oral ferric maltol and so weaken its effect on iron stores. Calcium carbonate also raises gastric pH and can bind iron in the gut.
What this interaction means in plain words
Calcium and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Ferric maltol belongs to Miscellaneous.
Why it happens
Reduced iron absorption through higher gastric pH and calcium competition for intestinal uptake.
What to do
Separate ferric maltol from calcium supplements or antacids by at least 2 hours, and check hemoglobin and ferritin to confirm response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
- Ciprofloxacin + Ferric maltol Moderate
Frequently asked questions
Can I take Calcium with Ferric maltol?
MediHelp rates the interaction as moderate. Calcium and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium salts may reduce the absorption of oral ferric maltol and so weaken its effect on iron stores. Calcium carbonate also raises gastric pH and can bind iron in the gut.
How serious is the interaction between Calcium and Ferric maltol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate ferric maltol from calcium supplements or antacids by at least 2 hours, and check hemoglobin and ferritin to confirm response.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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