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Drug interactions

Cimetidine + Ferric maltol

Severity: Moderate

Cimetidine and Ferric maltol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ferric maltol absorption may be reduced when gastric acid is suppressed. Reduced iron uptake could lessen response in iron-deficiency anemia.

What this interaction means in plain words

Cimetidine and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cimetidine belongs to Gastrointestinal Tract; Ferric maltol belongs to Miscellaneous.

Evidence level: Low

Why it happens

Cimetidine raises gastric pH, which may impair iron release and absorption.

What to do

Monitor hemoglobin and iron indices and consider whether acid suppression is still necessary.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cimetidine with Ferric maltol?

MediHelp rates the interaction as moderate. Cimetidine and Ferric maltol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ferric maltol absorption may be reduced when gastric acid is suppressed. Reduced iron uptake could lessen response in iron-deficiency anemia.

How serious is the interaction between Cimetidine and Ferric maltol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and iron indices and consider whether acid suppression is still necessary.

What other medicines interact with Cimetidine?

MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.

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