Drug interactions
Deferasirox + Ranolazine
Severity: Minor
Deferasirox and Ranolazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may modestly induce CYP3A4 and lower ranolazine exposure, potentially reducing antianginal effect. Evidence is limited and the effect is variable.
What this interaction means in plain words
Deferasirox and Ranolazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Ranolazine belongs to Cardiovascular.
Why it happens
Possible CYP3A4 induction by deferasirox increases ranolazine metabolism.
What to do
Monitor angina control and increase ranolazine only if symptoms worsen, within labeled dose limits.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deferasirox and Ranolazine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ranolazine
- Adagrasib + Ranolazine Contraindicated
- Amobarbital + Ranolazine Contraindicated
- Apalutamide + Ranolazine Contraindicated
- Butabarbital + Ranolazine Contraindicated
- Carbamazepine + Ranolazine Contraindicated
- Clarithromycin + Ranolazine Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Ranolazine?
MediHelp rates the interaction as minor. Deferasirox and Ranolazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may modestly induce CYP3A4 and lower ranolazine exposure, potentially reducing antianginal effect. Evidence is limited and the effect is variable.
How serious is the interaction between Deferasirox and Ranolazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor angina control and increase ranolazine only if symptoms worsen, within labeled dose limits.
What other medicines interact with Ranolazine?
MediHelp also lists interactions of Ranolazine with, for example, Adagrasib, Amobarbital, Apalutamide. The full list is on the Ranolazine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
