Drug interactions
Captopril-hydrochlorothiazide + Iron sucrose
Severity: Minor
Captopril-hydrochlorothiazide and Iron sucrose: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intravenous iron sucrose can cause transient hypotension during or shortly after infusion. Patients on antihypertensives such as captopril and hydrochlorothiazide may be more susceptible, although the effect is usually brief.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Iron sucrose have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Captopril-hydrochlorothiazide belongs to Cardiovascular; Iron sucrose belongs to Miscellaneous.
Why it happens
Additive blood pressure lowering with infusion-related hypotension from iron sucrose; mechanism is largely theoretical.
What to do
Monitor blood pressure during and after the infusion, and slow the infusion rate if hypotension develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Iron sucrose
- Dextrose 5% + Iron sucrose Contraindicated
- Deferasirox + Iron sucrose Moderate
- Deferiprone + Iron sucrose Moderate
- Deferoxamine + Iron sucrose Moderate
- Amlodipine-benazepril + Iron sucrose Minor
- Benazepril + Iron sucrose Minor
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Iron sucrose?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Iron sucrose have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intravenous iron sucrose can cause transient hypotension during or shortly after infusion. Patients on antihypertensives such as captopril and hydrochlorothiazide may be more susceptible, although the effect is usually brief.
How serious is the interaction between Captopril-hydrochlorothiazide and Iron sucrose?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during and after the infusion, and slow the infusion rate if hypotension develops.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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