Drug interactions
Deflazacort + Macimorelin
Severity: Moderate
Deflazacort and Macimorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can alter growth hormone secretion and may affect the reliability of the macimorelin growth hormone stimulation test. This could lead to misinterpretation of results.
What this interaction means in plain words
Deflazacort and Macimorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Macimorelin belongs to Endocrine.
Why it happens
Glucocorticoids suppress growth hormone release, which may confound the diagnostic response to macimorelin.
What to do
Interpret macimorelin results cautiously in patients on glucocorticoids and, where clinically feasible, allow an appropriate washout before testing.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deflazacort and Macimorelin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Macimorelin
Frequently asked questions
Can I take Deflazacort with Macimorelin?
MediHelp rates the interaction as moderate. Deflazacort and Macimorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids can alter growth hormone secretion and may affect the reliability of the macimorelin growth hormone stimulation test. This could lead to misinterpretation of results.
How serious is the interaction between Deflazacort and Macimorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret macimorelin results cautiously in patients on glucocorticoids and, where clinically feasible, allow an appropriate washout before testing.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
