Drug interactions
Deflazacort + Magnesium hydroxide
Severity: Minor
Deflazacort and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium hydroxide at laxative doses can cause diarrhea with potassium loss, and deflazacort adds renal potassium wasting. At usual antacid doses the effect is small.
What this interaction means in plain words
Deflazacort and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deflazacort belongs to Miscellaneous; Magnesium hydroxide belongs to Gastrointestinal Tract.
Why it happens
Additive potassium loss from diarrhea and corticosteroid-induced renal excretion.
What to do
Check potassium if magnesium hydroxide is used regularly at laxative doses or diarrhea develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Magnesium hydroxide?
MediHelp rates the interaction as minor. Deflazacort and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium hydroxide at laxative doses can cause diarrhea with potassium loss, and deflazacort adds renal potassium wasting. At usual antacid doses the effect is small.
How serious is the interaction between Deflazacort and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium if magnesium hydroxide is used regularly at laxative doses or diarrhea develops.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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