Drug interactions
Deflazacort + Mesterolone
Severity: Minor
Deflazacort and Mesterolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens such as mesterolone can promote sodium and fluid retention, which may add to the fluid retention caused by corticosteroids like deflazacort. This may increase edema, particularly in patients with heart, kidney or liver disease.
What this interaction means in plain words
Deflazacort and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deflazacort belongs to Miscellaneous; Mesterolone belongs to Endocrine.
Why it happens
Additive sodium and water retention from the androgen and the glucocorticoid.
What to do
Monitor body weight and signs of edema, and check blood pressure periodically in patients with cardiac or renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Mesterolone
Frequently asked questions
Can I take Deflazacort with Mesterolone?
MediHelp rates the interaction as minor. Deflazacort and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens such as mesterolone can promote sodium and fluid retention, which may add to the fluid retention caused by corticosteroids like deflazacort. This may increase edema, particularly in patients with heart, kidney or liver disease.
How serious is the interaction between Deflazacort and Mesterolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor body weight and signs of edema, and check blood pressure periodically in patients with cardiac or renal impairment.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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