Drug interactions
Deflazacort + Torsemide
Severity: Moderate
Deflazacort and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents promote potassium loss, so together they can cause clinically important hypokalemia. This may lead to weakness, arrhythmias and increased digoxin sensitivity where relevant.
What this interaction means in plain words
Deflazacort and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Torsemide belongs to Cardiovascular.
Why it happens
Additive renal potassium wasting from loop diuretic action and corticosteroid mineralocorticoid effect.
What to do
Monitor serum potassium regularly and supplement or add a potassium-sparing agent if levels fall.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Torsemide?
MediHelp rates the interaction as moderate. Deflazacort and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents promote potassium loss, so together they can cause clinically important hypokalemia. This may lead to weakness, arrhythmias and increased digoxin sensitivity where relevant.
How serious is the interaction between Deflazacort and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium regularly and supplement or add a potassium-sparing agent if levels fall.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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