Drug interactions
Delamanid + Ethambutol
Severity: Minor
Delamanid and Ethambutol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Co-administration increases ethambutol plasma concentrations by a modest amount. The clinical importance is uncertain, and the two are routinely used together in multidrug TB regimens.
What this interaction means in plain words
Delamanid and Ethambutol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Delamanid belongs to Anti Bacterial; Ethambutol belongs to Anti Bacterial.
Why it happens
The mechanism is not established.
What to do
No dose change needed; continue routine monitoring of visual acuity and colour vision during ethambutol therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Delamanid
- Carbamazepine + Delamanid Contraindicated
- Delamanid + Rifampicin Contraindicated
- Delamanid + Moxifloxacin Major
- Delamanid + Ritonavir Major
Other interactions of Ethambutol
- Allopurinol + Ethambutol Moderate
- Aluminum hydroxide / magnesium carbonate + Ethambutol Moderate
- Aluminum hydroxide / magnesium trisilicate + Ethambutol Moderate
- Bcg vaccine live + Ethambutol Moderate
- Ethambutol + Febuxostat Moderate
- Ethambutol + Probenecid Moderate
Frequently asked questions
Can I take Delamanid with Ethambutol?
MediHelp rates the interaction as minor. Delamanid and Ethambutol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-administration increases ethambutol plasma concentrations by a modest amount. The clinical importance is uncertain, and the two are routinely used together in multidrug TB regimens.
How serious is the interaction between Delamanid and Ethambutol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change needed; continue routine monitoring of visual acuity and colour vision during ethambutol therapy.
What other medicines interact with Delamanid?
MediHelp also lists interactions of Delamanid with, for example, Carbamazepine, Rifampicin, Moxifloxacin. The full list is on the Delamanid page.
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