Drug interactions
Desflurane + Eribulin
Severity: Moderate
Desflurane and Eribulin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin can prolong the QT interval and desflurane may add to the effect. The combination could increase the risk of torsades de pointes, particularly with electrolyte abnormalities.
What this interaction means in plain words
Desflurane and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desflurane belongs to Central Nervous System; Eribulin belongs to Oncology.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Check ECG and correct potassium and magnesium before anesthesia. Monitor the ECG perioperatively.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Desflurane
Other interactions of Eribulin
Frequently asked questions
Can I take Desflurane with Eribulin?
MediHelp rates the interaction as moderate. Desflurane and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval and desflurane may add to the effect. The combination could increase the risk of torsades de pointes, particularly with electrolyte abnormalities.
How serious is the interaction between Desflurane and Eribulin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and correct potassium and magnesium before anesthesia. Monitor the ECG perioperatively.
What other medicines interact with Desflurane?
MediHelp also lists interactions of Desflurane with, for example, Amisulpride, Anagrelide, Arsenic trioxide. The full list is on the Desflurane page.
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